Publications

45.
Small
Glueck D, Grethen A, Das M, Mmeka OP, Perez Patallo E, Meister A, Rajender R, Ahlhelm J, Kins S, Raeschle M, Victor J, Etzkorn M, Koeck Z, Bernhard F, Babalola JO, Vargas C, Keller S*
Electroneutral polymer nanodiscs enable interference-free probing of membrane proteins in a lipid-bilayer environment
Small (2022)
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44.
SR
Gopalswamy M, Kroeger T, Bickel D, Frieg B, Akter S, Schott-Verdugo S, Viegas A, Pauly T, Mayer M, Przibilla J, Reiners J, Nagel-Steger L, Smits SHJ, Groth G, Etzkorn M*, Gohlke H*
Biophysical and pharmacokinetic characterization of a small-molecule inhibitor of RUNX1/ETO tetramerization with anti-leukemic effects
Sci Rep 12, 1-18 (2022)
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43.
Nature
Borggräfe J, Victor, J, Rosenbach, H, Viegas A, Gertzen CGW, Wuebben C, Kovacs H, Gopalswamy M, Riesner D, Steger G, Schiemann O, Gohlke H, Span I, Etzkorn M*,
Time-resolved structural analysis of an RNA-cleaving DNA catalyst.
Nature 601, 144 (2022)
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- use this link for a free (read only) version -
42.
MIMB
Borggräfe J, Etzkorn M*,
Solution NMR Spectroscopy as a Tool to Study DNAzyme Structure and Function.
Methods in Molecular Biology 2436, 131-151 (2022)
- Get the protocol here -
41.
Biospektrum
Etzkorn M*,
Atomare Einblicke in die Dynamik der Membransysteme und der Biokatalyse.
Biospektrum 28, 30-33 (2022)
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40.
BC
Dubey A, Stoyanov N, Viennet T, Chhabra S, Elter S, Borggräfe J, Viegas A, Nowak RP, Burdzhiev N, Petrov O, Fischer ES, Etzkorn M*, Gelev V*, Arthanari H*
Local Deuteration Enables NMR Observation of Methyl Groups in Proteins from Eukaryotic and Cell-Free Expression Systems
Angew. Chem. Int. Ed. 60, 13783 (2021)
- Get the paper here (open access)-
- Cover Article -
39.
BC
Rosenbach H, Borggräfe J, Victor, Wubben C, Schiemann O, Hoyer W, Steger G, Etzkorn M*, Span I*
Influence of monovalent metal ions on metal binding and catalytic activity of the 10-23 DNAzyme
Biol. Chem. 402:99 (2021)
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38.
SR
Roesner N, Gremer L, Woerdehoff M, Kupreichyk T, Etzkorn M, Neudecker P, Hoyer, W
Clustering of human prion protein and α-synuclein oligomers requires the prion protein N-terminus
Commun Biol 3,365 (2020)
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37.
SR
Rosenbach H, Victor J, Etzkorn M, Steger G, Riesner D, Span I
Molecular Features and Metal Ions That Influence 10-23 DNAzyme Activity
Molecules 25:3100 (2020)
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36.
SR
Viegas A, Dollinger P, Verma N, Kubiak J, Viennet T, Seidel CAM, Gohlke H*, Etzkorn M*, Kovacic F, Jaeger KE*:
Structural and dynamic insights revealing how lipase binding domain MD1 of Pseudomonas aeruginosa foldase affects lipase activation
Sci Rep 10:3578 (2020)
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35.
JSB
Rosenbach H, Victor J, Borggräfe J, Biehl R, Steger G, Etzkorn M, Span I:
Expanding crystallization tools for nucleic acid complexes using U1A protein variants
J Struct Biol 2, 107480 (2020)
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34.
Structure
Viegas A, Yin DM, Borggräfe J, Viennet T, Falke M, Schmitz A, Famulok M, Etzkorn M:
Molecular Architecture of a Network of Potential Intracellular EGFR Modulators: ARNO, CaM, Phospholipids, and the Juxtamembrane Segment
Structure 28, 54-62 (2020)
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(cover article, January issue 2020)

33.
BMC
Porta N,Zaschke-Kriesche J, Frieg J, Gopalswamy M, Zivkovic A, Etzkorn M, Stark H, Smits S, Gohlke H:
Small-molecule inhibitors of nisin resistance protein NSR from the human pathogen Streptococcus agalactiae
Bioorg Med Chem 27, 115079 (2019)
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32.
CPL
Falke M, Victor J, Wördehoff MW, Peduzzo A, Zhang T, Schröder G, Buell AK, Hoyer W, Etzkorn M:
α-synuclein-derived lipoparticles in the study of α-Synuclein amyloid fibril formation
Chem Phys Lipids 220, 57-65, special issue 'lipid nanodiscs' (2019)
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31.
Frontiers
Viennet T, Bungert-Pümke S, Elter S, Viegas A, Fahlke C, Etzkorn M:
Reconstitution and NMR characterization of the ion-channel accessory subunit barttin in detergents and lipid-bilayer nanodiscs
Frontiers in Molecular Biosciences 6, 13 (2019)
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30.
BJ
Viennet T, Wördehoff MW, Uluca B, Poojari C, Shaykhalishahi H, Willbold D, Strodel B, Heise H, Buell AK, Hoyer W, Etzkorn M:
Structural insights from lipid-bilayer nanodiscs link α-Synuclein membrane-binding modes to amyloid fibril formation
Communications Biology 1, 44 (2018)
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29.
BJ
Uluca B, Viennet T, Petrovic D, Shaykhalishahi H, Weirich F, Gönülalan A, Strodel B, Etzkorn M, Hoyer W, Heise H:
DNP-Enhanced MAS NMR: A Tool to Snapshot Conformational Ensembles of α-Synuclein in Different States
Biophys J. 114, 1614-1623, (2018)
- Get the paper here (open access)-
PP.

BJ
Viennet T, Wördehoff MW, Uluca B, Poojari C, Shaykhalishahi H, Willbold D, Strodel B, Heise H, Buell AK, Hoyer W, Etzkorn M:
A structural and kinetic link between membrane association and amyloid fibril formation of α-Synuclein
bioRxiv (2017)
- Get the pre-print here -


28.
BJ
Bronder AM, Bieker A, Elter S, Etzkorn M, Häussinger D, Oesterhelt F:
Oriented Membrane Protein Reconstitution into Tethered Lipid Membranes for AFM Force Spectroscopy
Biophys. J. 111, 1925-1934, (2016)
- Get the paper here -
27.
BC
Viegas A, Viennet T, Etzkorn M:
The power, pitfalls and potential of the nanodisc system for NMR-based studies
Biol. Chem. 397, 1335-1354, (2016)
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26.
Angew
Viennet T, Viegas A, Kuepper A, Arens S, Gelev V, Petrov O, Grossmann TN, Heise H, Etzkorn M:
Selective Protein Hyperpolarization in Cell Lysates Using Targeted Dynamic Nuclear Polarization
Angew. Chem. Int. Ed. 55, 10746-10750, (2016)
- Get the paper here -
- Inside Cover Article -
25.
JBNMR
Viegas A, Viennet T, Yu TY, Schumann F, Bermel W, Wagner G, Etzkorn M:
UTOPIA NMR: activating unexploited magnetization using interleaved low-gamma detection.
J. Biomol. NMR 64, 9-15, (2016)
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24.
ismar
Elter S, Raschle T, Arens S, Viegas A, Gelev V, Etzkorn M, Wagner G:
The use of amphipols for NMR structural characterization of 7-TM proteins.
J. Membr. Biol. 247, 965-970, (2014)
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23.
ismar
Etzkorn M, Zoonens M, Catoire LJ, Popot JL, Hiller S:
How Amphipols Embed Membrane Proteins: Global Solvent Accessibility and Interaction with a Flexible Protein Terminus.
J. Membr. Biol. 247, 957-964, (2014)
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22.
ismar
Yi T, Zhai B, Yu Y, Kiyotsugu Y, Raschle T, Etzkorn M, Seo HC, Nagiec M, Luna RE, Reinherz EL, Blenis J, Gygi SP, Wagner G:
Quantitative phosphoproteomic analysis reveals system-wide signaling pathways downstream of SDF-1/CXCR4 in breast cancer stem cells.
PNAS 111(21), E2182-E2190 (2014)
- Get the paper here -
- See also PNAS highlight commentary -
21.
ismar
Etzkorn M, Raschle T, Hagn F, Gelev V, Rice A, Walz T, Wagner G:
Cell-Free Expressed Bacteriorhodopsin in Different Soluble Membrane Mimetics: Biophysical Properties and NMR Accessibility.
Structure 21, 394-401 (2013)
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20.
ismar
Hagn F, Etzkorn M, Raschle T, Wagner G:
Optimized phospholipid bilayer nanodiscs facilitate high-resolution structure determination of membrane proteins.
J. Am. Chem. Soc. 135, 1919-1925 (2013)
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- See also Science Editor's Choice -
19.
ismar
Müller H, Etzkorn M, Heise H:
Solid-State NMR Spectroscopy of Proteins.
Top. Curr. Chem. 335, 121-156 (2013)
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18.
ismar
Etzkorn M, Böckmann A, Baldus M:
Kinetic analysis of protein aggregation monitored by real-time 2D solid-state NMR.
J. biomol. NMR 49, 121-129 (2011)
- Get the paper here -
17.
ismar
Bardiaux B, Favier A, Etzkorn M, Baldus M, Böckmann A, Nilges M, Malliavin T:
Simultaneous use of solution, solid-state NMR and X-ray crystallography to study the conformational landscape of the Crh protein during oligomerization and crystallization.
Adv. Appl. Bioinf. Chem. 3, 25-38 (2010)
- Get the paper here -
16.
ismar
Etzkorn M, Seidel K, Li L, Martell S, Engelhard M, Baldus M:
Complex Formation and Light Activation in Membrane Embedded Sensory Rhodopsin II as Seen by Solid-State NMR Spectroscopy.
Structure 10, 293-300 (2010)
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15.
ismar
Kneuper H, Scheu PD, Etzkorn M, Sevvana M, Dünnwald P, Becker S, Baldus M, Griesinger C, Unden G:
Sensing Ligands by Periplasmic Sensing Histidine Kinases with Sensory PAS Domains.
Sensory Mechanisms in Bacteria Caister Academic Press, (2010)
- Get the review here -
14.
ismar
Raschle T, Hiller S, Etzkorn M, Wagner G:
Non-micellar systems for solution NMR spectroscopy of membrane proteins.
Curr. Opin. Struct. Biol. 20, 471-479 (2010)
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13.
ismar
Schneider R, Etzkorn M, Giller K, Daebel V, Eisfeld J, Zweckstetter M, Griesinger C, Becker S, Lange A:
The Native Conformation of the Human VDAC1 N Terminus.
Angew. Chem. Int. Ed. 49, 1882-1885 (2010)
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12.
ismar
Schneider R, Seidel K, Etzkorn M, Lange A, Becker S, Baldus M:
Probing molecular motion by double-quantum (13C,13C) solid-state NMR spectroscopy: application to ubiquitin.
J. Am. Chem. Soc. 132, 223-233 (2010)
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11.
ismar
Ader C, Schneider R, Seidel K, Etzkorn M, Becker S, Baldus M:
Structural rearrangements of membrane proteins probed by water-edited solid-state NMR spectroscopy.
J. Am. Chem. Soc. 131, 170-176 (2009)
- Get the paper here -
10.
ismar
Seidel K, Etzkorn M, Schneider R, Ader C, Baldus M:
Comparative Analysis of NMR Chemical Shift Predictions for Proteins in the Solid Phase.
Solid State Nucl. Magn. Res. 35, 235-242 (2009)
- Get the paper here -
9.
ismar
Etzkorn M, Kneuper H, Dünnwald P, Vijaian V, Griesinger C, Becker S, Unden G, Baldus M:
Plasticity of the PAS domain and a potential role for signal transduction in the histidine kinase DcuS.
Nat. Struct. Mol. Biol. 15, 1031-1039 (2008)
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(selected as "Article of the month")
8.
ismar
Gardiennet C, Loquet A, Etzkorn M, Heise H, Baldus M, Böckmann A:
Structural constraints for the Crh protein from solid-state NMR.
J. biomol. NMR 4035, 239-250 (2008)
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7.
ismar
Ader C, Schneider R, Seidel K, Etzkorn M, Baldus, M:
Magic-angle-spinning NMR spectroscopy applied to small molecules and peptides in lipid bilayers.
Biochem. Soc. Trans. 35, 991-995 (2007)
- Get the review here -
6.
ismar
Etzkorn M, Böckmann A, Penin F, Riedel D, Baldus M:
Characterization of folding intermediates of a domain-swapped protein by solid-state NMR spectroscopy.
J. Am. Chem. Soc. 129, 169-175 (2007)
- Get the paper here -
5.
ismar
Etzkorn M, Martell S, Andronesi OC, Seidel K, Engelhard M, Baldus M:
Secondary structure and topology of a seven-helix receptor in native membranes studied by solid-state NMR.
Angew. Chem. Int. Ed. 46, 459-462 (2007)
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- Cover Article -
4.
ismar
Heise H, Seidel K, Etzkorn M, Becker S, Baldus M:
3D MAS Solid-state NMR spectroscopy for resonance assignment and structure elucidation of proteins. Novel pulse schemes and sensitivity considerations.
J. Magn. Res. 173, 65-74 (2005)
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3.
ismar
Seidel K, Etzkorn M, Heise H, Becker S, Baldus M:
High-resolution solid-state NMR studies on uniformly [13C,15N]-labeled ubiquitin.
ChemBioChem 6, 1638-1647 (2005)
- Get the paper here -
2.
ismar
Seidel K, Etzkorn M, Sonnenberg L, Griesinger C, Sebald A, Baldus M:
Studying 3D structure and dynamics by high resolution solid-state NMR: Application to L-Tyrosine-Ethylester.
J. Phys. Chem. A 109, 2436-2442 (2005)
- Get the paper here -
1.
ismar
Etzkorn M, Böckmann A, Lange A, Baldus M:
Probing molecular interfaces using 2D magic-angle-spinning NMR on protein mixtures with di¬fferent uniform labeling.
J. Am. Chem. Soc. 126, 14746-14751 (2004)
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